1. Volume 115, Issue 6, Pages 1346-1352 (December 1998)
Role of impaired gastric accommodation to a meal in functional dyspepsia 
Jan Tack, Hubert Piessevaux, Bernard Coulie, Philip Caenepeel, Jozef Janssens 
Gastroenterology 
Volume 115, Issue 6, Pages (December 1998)
DOI: /S (98)
Copyright © 1998 American Gastroenterological Association Terms and Conditions

2. Fig. 1
Mean intragastric volume at 5-minute intervals as measured by a gastric barostat in healthy volunteers before and after administration of a mixed liquid meal (time 0). Ingestion of the meal induces a rapid and sustained increase in intragastric volume, reflecting a relaxation of the gastric fundus. The number of volunteers at each data point is 35 before the meal and during the first postprandial hour and 25 for the second postprandial hour. The postprandial intragastric volume was significantly greater than the mean preprandial volume at each point from 5 to 115 minutes after the meal.
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

3. Fig. 2
Gastric accommodation to a meal, quantified as the difference between the average volumes during the 30 minutes before and 60 minutes after the administration of the meal, in 40 patients with functional dyspepsia and 35 healthy controls. Individual values are shown as dots; mean and SEM for each group are shown as bars. A subset of the patients have a meal-induced gastric relaxation below the normal range, indicated by the two horizontal bars.
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

4. Fig. 3
Dyspepsia symptoms in 40 consecutive patients with functional dyspepsia. The figure shows the number of patients grading individual symptoms as relevant or severe (score of ≥2) in the subgroups with normal (□) or impaired (▨) gastric accommodation. Early satiety and weight loss of >5% of the initial body weight were significantly more prevalent in patients with impaired accommodation to a meal.
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

5. Fig. 4
Influence of sumatriptan on postprandial gastric relaxation and on meal-induced satiety in patients with functional dyspepsia and impaired gastric accommodation to a meal. (A) Meal-induced gastric relaxation is expressed as the mean increase in intraballoon volume during 60 minutes after the meal, measured with a gastric barostat. In 6 patients, administration of 6 mg sumatriptan subcutaneously before the meal significantly increased the meal-induced gastric relaxation. (B) In 10 patients, preprandial administration of 6 mg sumatriptan subcutaneously significantly increased the amount of calories inducing maximum satiety.
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions