1. Percent Free Prostate-Specific Antigen: Entering a New Era in the Detection of Prostate Cancer 
Apoorva R. Vashi, M.D., Joseph E. Oesterling, M.D. 
Mayo Clinic Proceedings 
Volume 72, Issue 4, Pages (April 1997)
DOI: /
Copyright © 1997 Mayo Foundation for Medical Education and Research Terms and Conditions

2. Fig. 1
Determination of prostate-specific antigen (PSA) reflex range with best performance for percent free PSA. Bar graph illustrates that total PSA range of 3.0 to 10.0 ng/mL demonstrates maximal improvement of percent free PSA over total PSA. (From Vashi and colleagues.38 By permission.)
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3. Fig. 2
Receiver operating characteristic curves for distinguishing prostate cancer from benign prostate disease, comparing percent free prostate-specific antigen (PSA) to total PSA in reflex range subset of 3.0 to 4.0 ng/mL. Areas under the receiver operating characteristic curves for percent free PSA and total PSA are 0.78 and 0.40, respectively (P<0.01). (From Vashi and associates.38 By permission.)
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Copyright © 1997 Mayo Foundation for Medical Education and Research Terms and Conditions

4. Fig. 3
Receiver operating characteristic curves for distinguishing prostate cancer from benign prostate disease, comparing percent free prostate-specific antigen (PSA) to total PSA in reflex range subset of 4.1 to 10.0 ng/mL. Areas under the receiver operating characteristic curves for percent free PSA and total PSA are 0.71 and 0.52, respectively (P<0.05). (From Vashi and coworkers.38 By permission.)
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Copyright © 1997 Mayo Foundation for Medical Education and Research Terms and Conditions

5. Fig. 4
Diagnostic algorithm for detecting early, curable prostate cancer by using percent free prostate-specific antigen (PSA). DRE = digital rectal examination; TRUS = transrectal ultrasonographic.
Mayo Clinic Proceedings  , DOI: ( / )
Copyright © 1997 Mayo Foundation for Medical Education and Research Terms and Conditions