1. Tracing Stem Cell Division in Adult Neurogenesis
Nina S. Corsini, Juergen A. Knoblich 
Cell Stem Cell 
Volume 22, Issue 2, Pages (February 2018)
DOI: /j.stem
Copyright © 2018 Elsevier Inc. Terms and Conditions

2. Figure 1
Symmetric Differentiation and Self-Renewal in the V-SVZ of the Adult Mouse Brain
(A) Scheme depicting a sagittal view of the adult mouse brain. OB, olfactory bulb; V-SVZ, ventricular-subventricular zone; LV, later ventricles; RMS, rostral migratory stream.
(B) Close-up scheme of the V-SVZ. B1 cells reside in the V-SVZ and contact the LV as well as blood vessels. B2 cells have no contact to the ventricle. B1 cells give rise to C cells, which differentiate into A cells. NSC, neural stem cell.
(C and D) Modes of division observed in the V-SVZ. (C) 20% of divisions observed are symmetric self-renewing divisions that generate either two B1 cells or two B2 cells. (D) 80% of divisions observed are symmetric consuming divisions that generate two C cells.
Cell Stem Cell  , DOI: ( /j.stem )
Copyright © 2018 Elsevier Inc. Terms and Conditions