1. Polymorphisms in the Tyrosine Kinase 2 and Interferon Regulatory Factor 5 Genes Are Associated with Systemic Lupus Erythematosus 
Snaevar Sigurdsson, Gunnel Nordmark, Harald H.H. Göring, Katarina Lindroos, Ann-Christin Wiman, Gunnar Sturfelt, Andreas Jönsen, Solbritt Rantapää-Dahlqvist, Bozena Möller, Juha Kere, Sari Koskenmies, Elisabeth Widén, Maija-Leena Eloranta, Heikki Julkunen, Helga Kristjansdottir, Kristjan Steinsson, Gunnar Alm, Lars Rönnblom, Ann-Christine Syvänen 
The American Journal of Human Genetics 
Volume 76, Issue 3, Pages (March 2005)
DOI: /428480
Copyright © 2005 The American Society of Human Genetics Terms and Conditions

2. Figure 1
Schematic illustration of the structure of TYK2 and IRF5. The positions of exons are shown as numbered gray boxes, and the translation initiation sites are shown by arrows on both genes. The positions of the 11 TYK2 SNPs and the 6 IRF5 SNPs analyzed in the study are shown by vertical lines and dbSNP rs numbers. SNPs with low P values in joint linkage and association analysis in the Swedish and/or Finnish sample sets are marked with an asterisk (*). The D′ and r2 values for pairwise linkage disequilibrium for the TYK2 SNPs were calculated from the genotypes of Swedish unrelated control individuals, and the D′ and r2 values for the IRF5 SNPs were calculated from Finnish unrelated control individuals, by use of the Haploview program (Barrett et al. 2005). ns=nonsignificant.
The American Journal of Human Genetics  , DOI: ( /428480)
Copyright © 2005 The American Society of Human Genetics Terms and Conditions

3. Figure A1
Pairwise LD values determined using the Haploview program for 11 SNPs in the tyrosine kinase 2 (TYK2) gene and 6 SNPs in the IFN regulatory factor 5 (IRF5) gene in control individuals from the Swedish population (n=256) and the Finnish population (n=121). The dbSNP rs numbers for the SNPs are given to the left and above the boxes in the diagrams. D′ values are given in the lower left half and R2 values in the upper right half of the diagrams.
The American Journal of Human Genetics  , DOI: ( /428480)
Copyright © 2005 The American Society of Human Genetics Terms and Conditions