1. Meddling with METTLs in Normal and Leukemia Stem Cells
Gaëlle H. Martin, Christopher Y. Park 
Cell Stem Cell 
Volume 22, Issue 2, Pages (February 2018)
DOI: /j.stem
Copyright © 2018 Elsevier Inc. Terms and Conditions

2. Figure 1
Model of METTL3-METTL14-Dependent Myeloid Differentiation in Normal and Leukemic Hematopoietic Cells
METTL3 and METTL14 are highly expressed in HSCs and their expression is decreased during myeloid differentiation. In AML, upregulation of METTL3 and METTL14 results in increased methylation of their target transcripts including specific mRNAs critical for the regulation of apoptosis and differentiation.
Cell Stem Cell  , DOI: ( /j.stem )
Copyright © 2018 Elsevier Inc. Terms and Conditions