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Volume 119, Issue 4, Pages (October 2000)

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Presentation on theme: "Volume 119, Issue 4, Pages (October 2000)"— Presentation transcript:

1 Volume 119, Issue 4, Pages 909-920 (October 2000)
Genetic factors determine extent of bone loss in inflammatory bowel disease  Claudia M.S. Schulte, Axel U. Dignass, Harald Goebell, Hans–Dietrich Röher, Klaus–Martin Schulte  Gastroenterology  Volume 119, Issue 4, Pages (October 2000) DOI: /gast Copyright © 2000 American Gastroenterological Association Terms and Conditions

2 Fig. 1 Amplified variable number tandem repeat polymorphism of IL-1ra gene. The products of 7 patients after electrophoresis in 0.8% agarose. Lanes 1, 4, and 7, homozygotes 410/410; lane 2, heterozygote 240/500; lane 3, heterozygote 240/410; lane 5, heterozygote 410/500; lane 6, homozygote 240/240; lane 8, molecular weight marker. Gastroenterology  , DOI: ( /gast ) Copyright © 2000 American Gastroenterological Association Terms and Conditions

3 Fig. 2 Fragment length polymorphism in amplimers of hsp 70-2 gene. The hsp 70-2 PCR products were digested with PstI. The hsp P1 allele corresponds to the 244- and 139-bp fragments (cleavage of the 383-bp fragment). The hsp P2 allele corresponds to the 383-bp fragment (absence of the PstI site). The products of digestion reactions after electrophoresis in 1.0% agarose are shown. Lane M, molecular weight marker; lane 1, homozygotes P1/P1; lanes 2 and 3, heterogygotes P1/P2. Gastroenterology  , DOI: ( /gast ) Copyright © 2000 American Gastroenterological Association Terms and Conditions

4 Fig. 3 Amplified CG-tandem repeat of the IL-6 gene. A product separated by electrophoresis on 8% polyacrylamide sequencing gels. The arrow indicates the internal standard of 100 bp; the product is a heterozygote 120/122. Gastroenterology  , DOI: ( /gast ) Copyright © 2000 American Gastroenterological Association Terms and Conditions


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