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Changes over time in (A) waist circumference, (B) BMI, (C) ALT, (D) Matsuda index, (E) AUCglucagon, and (F) ISSI-2, comparing patients with drug-free diabetes remission at 48 weeks and those not in remission at 48 weeks (solid square: remission; open circle... Changes over time in (A) waist circumference, (B) BMI, (C) ALT, (D) Matsuda index, (E) AUCglucagon, and (F) ISSI-2, comparing patients with drug-free diabetes remission at 48 weeks and those not in remission at 48 weeks (solid square: remission; open circle: non-remission). ALT, alanine aminotransferase; AUCglucagon, area-under-the-glucagon-curve; BMI, body mass index; ISSI-2, Insulin Secretion-Sensitivity Index-2; pre-IIT, prior to intensive insulin therapy; post-IIT, after intensive insulin therapy; p values are for differences between groups. Caroline K Kramer et al. BMJ Open Diab Res Care 2016;4:e000270 ©2016 by American Diabetes Association
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