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Does OSA Upregulate Cardioprotective Pathways to an Ischemic Insult?

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Presentation on theme: "Does OSA Upregulate Cardioprotective Pathways to an Ischemic Insult?"— Presentation transcript:

1 Does OSA Upregulate Cardioprotective Pathways to an Ischemic Insult?
Doron Aronson, MD, Lena Lavie, PhD, Peretz Lavie, PhD  CHEST  Volume 153, Issue 2, Pages (February 2018) DOI: /j.chest Copyright © 2017 American College of Chest Physicians Terms and Conditions

2 Figure 1 The clinical consequences of intermittent hypoxia (IH) are determined by a complex interaction between multiple factors, including the extent of the maladaptive and adaptive responses to IH as well as the individual patient susceptibility to the deleterious effects of IH and the specific organ or vascular bed. CAD = coronary artery disease; EPCs = endothelial progenitor cells; HIF-1α = hypoxia-inducible factor-1α; HSPs = heat shock proteins; LVH = left ventricular hypertrophy; VEGF = vascular endothelial growth factor. CHEST  , DOI: ( /j.chest ) Copyright © 2017 American College of Chest Physicians Terms and Conditions


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