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Published byHendra Widjaja Modified over 5 years ago
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Are Combinations the Solution: Perspectives on Combination Immunotherapy
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This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the United States, and data that were presented in abstract form. These data should be considered preliminary until published in a peer-reviewed journal.
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Immunotherapy: Paradigm on the Rise
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MOA of Inhibitors on PD-1 Pathway
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FDA Approved PD-1/PD-L1 Inhibitors
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Toxicity With PD-1/PD-L1 Inhibitors
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Predictive Biomarkers Are Lacking
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PD-1 and CTLA-4 Inhibition in Melanoma
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CheckMate 069
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What About Other Tumors?
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CheckMate 012
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Durvalumab/Tremelimumab in NSCLC
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Toxicity in a Broader Population
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Immunotherapy Is Not Chemotherapy
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Immunotherapy/Immunotherapy Summary
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Chemoimmunotherapy
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KEYNOTE 021
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KEYNOTE 024
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Chemotherapy/Immunotherapy Summary
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Overcoming Challenges of Targeted Therapies
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PD-1/BRAF/MEK Inhibition in Melanoma
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PD-1/EGFR Inhibition in NSCLC
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TATTON Results: EGFR/PD-L1 Inhibition
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Is Immunotherapy the Right Approach?
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Mutational Load in Never Smokers
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Targeted Therapy/Immunotherapy Summary
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Overall Conclusions
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Abbreviations
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