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Epithelial Contractility: A Crowning Achievement

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Presentation on theme: "Epithelial Contractility: A Crowning Achievement"— Presentation transcript:

1 Epithelial Contractility: A Crowning Achievement
Jeanne N. Jodoin, Adam C. Martin  Developmental Cell  Volume 37, Issue 1, Pages 3-4 (April 2016) DOI: /j.devcel Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Junctional Actomyosin Reorganization Required for Contractility (A) A mature actomyosin network is present at cell-cell contacts. (B) Following F-actin depolymerization, junctional actomyosin network is organized via two steps: actomyosin nucleation and actomyosin alignment. (C) Apoptosis (purple cell) produces a mechanical stimulus that recruits Coro1B to junctions through E-cadherin to upregulate and align junctional actomyosin and drive apoptotic cell extrusion. Developmental Cell  , 3-4DOI: ( /j.devcel ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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