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Dendritic cells and innate immunity in kidney transplantation
Quan Zhuang, Fadi G. Lakkis Kidney International Volume 87, Issue 4, Pages (April 2015) DOI: /ki Copyright © 2015 International Society of Nephrology Terms and Conditions
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Figure 1 Innate allorecognition and danger link innate to adaptive immunity after transplantation. Recognition of allogeneic non-self by recipient monocytes is key for generating mature DCs that drive graft rejection by T lymphocytes. Danger, which causes inflammation in the graft but is not sufficient for driving rejection, is nevertheless essential for potentiating the adaptive alloimmune response. Kidney International , DOI: ( /ki ) Copyright © 2015 International Society of Nephrology Terms and Conditions
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