1. Progression of Unresected Intraductal Papillary Mucinous Neoplasms of the Pancreas to Cancer: A Systematic Review and Meta-analysis 
Sang Hyun Choi, Seong Ho Park, Kyung Won Kim, Ja Youn Lee, Sang Soo Lee 
Clinical Gastroenterology and Hepatology 
Volume 15, Issue 10, Pages e4 (October 2017)
DOI: /j.cgh
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2. Figure 1
Flow diagram of the article selection process. An article may have been excluded for multiple reasons, but only 1 major reason per article is presented. *The sum (9 + 10) is not 17 because 2 articles reported results separately for the low-risk and non–low-risk patient groups; hence, these results were considered as separate studies for the meta-analysis.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
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3. Figure 2
Meta-analytic summary of cumulative incidence of pancreatic cancer. (A) Forest plot for studies of low-risk IPMN. Study ID provides the first author's name and year of publication. Diamond marker indicates the meta-analytic summary estimate of cumulative incidence of pancreatic cancer (%). (B) Forest plot for studies of non–low-risk IPMN. (C) Meta-analytic estimates of cumulative incidence across the follow-up periods. Error bars represent 95% CI.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
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4. Figure 3
Funnel plots to evaluate publication bias. (A) Studies of low-risk IPMN. (B) Studies of non–low-risk IPMN.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
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5. Supplementary Figure 1
Summary of quality of the included articles. Quality of the articles is presented as the proportion of articles (0%−100%) for each variable.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
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6. Supplementary Figure 2
Meta-analytic results of a subgroup of studies of low-risk IPMN, which fulfilled the clearer definition for low risk. (A) Forest plot. Study ID provides first author's name and year of publication. Diamond marker indicates meta-analytic summary estimate of cumulative incidence (%) of pancreatic cancer. (B) Meta-analytic estimates of cumulative incidence across follow-up time points are displayed graphically. Error bars represent 95% CI.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
Copyright © 2017 AGA Institute Terms and Conditions

7. Supplementary Figure 2
Meta-analytic results of a subgroup of studies of low-risk IPMN, which fulfilled the clearer definition for low risk. (A) Forest plot. Study ID provides first author's name and year of publication. Diamond marker indicates meta-analytic summary estimate of cumulative incidence (%) of pancreatic cancer. (B) Meta-analytic estimates of cumulative incidence across follow-up time points are displayed graphically. Error bars represent 95% CI.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
Copyright © 2017 AGA Institute Terms and Conditions

8. Supplementary Figure 3
Meta-analytic results of high-quality subgroup of the studies of low-risk IPMN. (A) Forest plot. Study ID provides first author's name and year of publication. Diamond marker indicates meta-analytic summary estimate of cumulative incidence (%) of pancreatic cancer. (B) Meta-analytic estimates of cumulative incidence across the follow-up time points are displayed graphically. Error bars represent 95% CI.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
Copyright © 2017 AGA Institute Terms and Conditions

9. Supplementary Figure 3
Meta-analytic results of high-quality subgroup of the studies of low-risk IPMN. (A) Forest plot. Study ID provides first author's name and year of publication. Diamond marker indicates meta-analytic summary estimate of cumulative incidence (%) of pancreatic cancer. (B) Meta-analytic estimates of cumulative incidence across the follow-up time points are displayed graphically. Error bars represent 95% CI.
Clinical Gastroenterology and Hepatology  , e4DOI: ( /j.cgh )
Copyright © 2017 AGA Institute Terms and Conditions