1. Perfecting the ring and extending the antibacterial spectrum: ‘the multiple generations’ 
A. Bryskier 
Clinical Microbiology and Infection 
Volume 6, Pages (January 2000)
DOI: /j tb02035.x
Copyright © 2000 European Society of Clinical Infectious Diseases Terms and Conditions

2. Figure 1 Discovery of cephalosporin C.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
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3. Figure 2
Cephems: classification 2, chemical classification 1, modification of the ring.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
Copyright © 2000 European Society of Clinical Infectious Diseases Terms and Conditions

4. Figure 3
Cephems: classification 3, chemical classification 2, modification of substituents.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
Copyright © 2000 European Society of Clinical Infectious Diseases Terms and Conditions

5. Figure 4 Successive waves of cephems.
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Copyright © 2000 European Society of Clinical Infectious Diseases Terms and Conditions

6. Figure 5 Cephems: microbiological classification.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
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7. Figure 6 Cephems: pharmacokinetics classification.
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8. Figure 7 Cephems: classification: five subgroups A–E.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
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9. Figure 8 Cephems group III.
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10. Figure 9 Cephem group III.
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11. Figure 10
Group III B cephems with long apparent elimination half-life.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
Copyright © 2000 European Society of Clinical Infectious Diseases Terms and Conditions

12. Figure 11 Cephems: group III; Oxa-1-cephems.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
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13. Figure 12 Cephems zwitterionic compounds.
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14. Figure 13 Cephems: group IV (2) classification.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
Copyright © 2000 European Society of Clinical Infectious Diseases Terms and Conditions

15. Figure 14 Group IV C-3′ ammonium quaternary cephems.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
Copyright © 2000 European Society of Clinical Infectious Diseases Terms and Conditions

16. Figure 15 Cephems group IV: chemical alteration.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
Copyright © 2000 European Society of Clinical Infectious Diseases Terms and Conditions

17. Figure 16 Cephems: group V (2): classification
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
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18. Figure 17 Cephems: group V.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
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19. Figure 18 Cephems: group VII: cephems designed for anti-MRSA activity.
Clinical Microbiology and Infection 2000 6, 13-21DOI: ( /j tb02035.x)
Copyright © 2000 European Society of Clinical Infectious Diseases Terms and Conditions