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Ultrasound-guided regional anesthesia for carotid endarterectomy induces early hemodynamic and stress hormone changes  Judith Hoefer, MD, MSc, Eve Pierer,

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Presentation on theme: "Ultrasound-guided regional anesthesia for carotid endarterectomy induces early hemodynamic and stress hormone changes  Judith Hoefer, MD, MSc, Eve Pierer,"— Presentation transcript:

1 Ultrasound-guided regional anesthesia for carotid endarterectomy induces early hemodynamic and stress hormone changes  Judith Hoefer, MD, MSc, Eve Pierer, MD, Barbara Rantner, MD, Karl-Heinz Stadlbauer, MD, Gustav Fraedrich, MD, Josef Fritz, Dipl Ing, Axel Kleinsasser, MD, Corinna Velik-Salchner, MD  Journal of Vascular Surgery  Volume 62, Issue 1, Pages (July 2015) DOI: /j.jvs Copyright © 2015 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Study flow chart. GA, General anesthesia; RA, locoregional anesthesia; t, time. Journal of Vascular Surgery  , 57-67DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Consolidated Standards of Reporting Trials (CONSORT) flow diagram. Journal of Vascular Surgery  , 57-67DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

4 Fig 3 Intraoperative systolic blood pressure (SBP) in patients undergoing carotid endarterectomy (CEA) with regional anesthesia (RA) or general anesthesia (GA) at baseline (t0), after induction of anesthesia (t1), before cross-clamping (t2), after cross-clamping (t3), and 1 hour after admission to the postanesthesia care unit (t4). Data are presented as mean ± standard deviation. *P < .05, **P < .001; NS, Not significant. Journal of Vascular Surgery  , 57-67DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

5 Fig 4 Heart rate (HR) in patients undergoing carotid endarterectomy (CEA) with regional anesthesia (RA) or general anesthesia (GA) at baseline (t0), after induction of anesthesia (t1), before cross-clamping (t2), after cross-clamping (t3), and 1 hour after admission to the postanesthesia care unit (t4). Data are presented as mean ± standard deviation. **P < .001; NS, Not significant. Journal of Vascular Surgery  , 57-67DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

6 Fig 5 Plasma cortisol (normal values are shaded) in patients undergoing carotid endarterectomy (CEA) with regional anesthesia (RA) or general anesthesia (GA) at baseline (t0), after induction of anesthesia (t1), before cross-clamping (t2), after cross-clamping (t3), and 1 hour after admission to the postanesthesia care unit (t4). Data are presented as mean ± standard deviation. *P < .05, **P < .001; NS, Not significant. Journal of Vascular Surgery  , 57-67DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

7 Fig 6 Plasma metanephrine (normal values are shaded) in patients undergoing carotid endarterectomy (CEA) with regional anesthesia (RA) or general anesthesia (GA) at baseline (t0), after induction of anesthesia (t1), before cross-clamping (t2), after cross-clamping (t3), and 1 hour after admission to the postanesthesia care unit (t4). Data are presented as mean ± standard deviation. No differences between groups were detected. NS, Not significant. Journal of Vascular Surgery  , 57-67DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

8 Fig 7 Plasma normetanephrine (normal values are shaded) in patients undergoing carotid endarterectomy (CEA) with regional anesthesia (RA) or general anesthesia (GA) at baseline (t0), after induction of anesthesia (t1), before cross-clamping (t2), after cross-clamping (t3), and 1 hour after admission to the postanesthesia care unit (t4). Data are presented as mean ± standard deviation. No differences between groups were detected. NS, Not significant. Journal of Vascular Surgery  , 57-67DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

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