1. Bay 38-7690 induces aberrant assembly of Cp
Bay induces aberrant assembly of Cp. (A) Purified HBV C150 (18 µM dimer) was assembled in the presence of DMSO or 10 µM Bay and analyzed by TEM. Bars, 50 nm.
Bay induces aberrant assembly of Cp. (A) Purified HBV C150 (18 µM dimer) was assembled in the presence of DMSO or 10 µM Bay and analyzed by TEM. Bars, 50 nm. (B) C150 (7.5 µM dimer) was assembled in the presence of 0 to 50 µM Bay and analyzed by DLS. Results were plotted using GraphPad Prism 5.0 and analyzed with the “log(agonist) versus normalized response − variable slope” equation. The values represent mean ± standard error of the mean from two independent experiments.
Andrew D. Huber et al. mSphere 2018; doi: /mSphereDirect