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Transluminal stent graft repair with Wallgraft endoprosthesis in a porcine arteriovenous graft pseudoaneurysm model  Peter H. Lin, MD, Chris K. Johnson,

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Presentation on theme: "Transluminal stent graft repair with Wallgraft endoprosthesis in a porcine arteriovenous graft pseudoaneurysm model  Peter H. Lin, MD, Chris K. Johnson,"— Presentation transcript:

1 Transluminal stent graft repair with Wallgraft endoprosthesis in a porcine arteriovenous graft pseudoaneurysm model  Peter H. Lin, MD, Chris K. Johnson, MD, Jennifer K. Pullium, DVM, Alan J. Koffron, MD, Brian Conklin, PhD, Thomas T. Terramani, MD, Ruth Bush, MD, Changyi Chen, MD, PhD, Alan B. Lumsden, MD  Journal of Vascular Surgery  Volume 37, Issue 1, Pages (January 2003) DOI: /mva Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

2 Fig. 1 Experimental AVG pseudoaneurysm model used in our study is created with 6-mm polytetrafluoroethylene graft in femoral arteriovenous circulation with interposing 12-mm Dacron graft in middle, which created overdilated pseudoaneurysm segment shown on arteriogram. Journal of Vascular Surgery  , DOI: ( /mva ) Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

3 Fig. 2 Four weeks after AVG creation, Wallgraft was inserted to exclude AVG pseudoaneurysm. Hemodialysis was perforemd with puncture of Wallgraft with two 15-gauge needles to maintain flow rate of 400 mL/min for 1 hour. Hemodialysis was performed in each animal every 4 days for a total of 6 weeks. Journal of Vascular Surgery  , DOI: ( /mva ) Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

4 Fig. 3 In vitro fluid circuitry. A, Flow-regulated faucet provides inflow water source; B, AVG pseudoaneurysm, which has been excluded with Wallgraft; C, 5F catheter measures pressure within Wallgraft fluid circuitry; D, another 5F catheter measures peri-Wallgraft endoleak, or flow within pseudoaneurysm; E, double-channeled pressure transducer monitor records pressures from both Wallgraft and pseudoaneurysm; and F, roller pump provides pulsatile pressure within fluid circuit. Journal of Vascular Surgery  , DOI: ( /mva ) Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

5 Fig. 4 Flow-pressure curve shows maximal pulsatile flow within in vitro flow circuitry without peri-Wallgraft endoleak (PWE). Journal of Vascular Surgery  , DOI: ( /mva ) Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

6 Fig. 5 SEM of luminal surface of explanted Wallgraft revealed thin neointimal layer consisting of thrombus and scattered platelet (white arrow) and red blood cell deposition (black arrow). Journal of Vascular Surgery  , DOI: ( /mva ) Copyright © 2002 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

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