1. Zika Virus Infection RIG-ged by Keratinocytes and Fibroblasts
Nicolas Dupin, Vincent Piguet 
Journal of Investigative Dermatology 
Volume 139, Issue 2, Pages (February 2019)
DOI: /j.jid
Copyright © 2018 The Authors Terms and Conditions

2. Figure 1
Zika virus interaction with skin cells. (1) ZIKV infects both keratinocyte and fibroblasts. (2) ZIKV can activate the RLR pathways and (3) induce secretion of interferon, which is an antiviral molecule and (4) may partially control the infection. (5) In response, the NS1 protein of ZIKV can inhibit activation of RLRs, allowing the virus to partially escape from the immune host defense. FB, fibroblast; KC, keratinocyte; RLR, retinoic acid-inducible gene receptor; ZIKV, Zika virus.
Journal of Investigative Dermatology  , DOI: ( /j.jid )
Copyright © 2018 The Authors Terms and Conditions