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A 49-Year-Old Woman With Right Apical Thoracic Mass

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Presentation on theme: "A 49-Year-Old Woman With Right Apical Thoracic Mass"— Presentation transcript:

1 A 49-Year-Old Woman With Right Apical Thoracic Mass
Yevgeniy A. Linnik, MD, Dagmar Hoegemann Savellano, MD, Joseph D. Phillips, MD, Candice C. Black, DO  CHEST  Volume 152, Issue 6, Pages e133-e138 (December 2017) DOI: /j.chest Copyright © 2017 American College of Chest Physicians Terms and Conditions

2 Figure 1 Chest posteroanterior radiograph shows a large convex density at the medial right apex. CHEST  , e133-e138DOI: ( /j.chest ) Copyright © 2017 American College of Chest Physicians Terms and Conditions

3 Figure 2 CT scanning showed a well-circumscribed, homogeneous 6-cm mass at the medial apex of the right hemithorax with extension into the upper mediastinum along the trachea, in between the trachea and esophagus, and along the right subclavian vessels. CHEST  , e133-e138DOI: ( /j.chest ) Copyright © 2017 American College of Chest Physicians Terms and Conditions

4 Figure 3 T1-weighted MRI scan with spectral fat saturation after intravenous contrast enhancement showed diffuse heterogeneous enhancement of the mass. It confirmed its well-circumscribed borders without any evidence of invasion into adjacent structures. CHEST  , e133-e138DOI: ( /j.chest ) Copyright © 2017 American College of Chest Physicians Terms and Conditions

5 Figure 4 MRI showed a well-circumscribed, slightly heterogeneous mass, which was hypointense on T1-weighted images and hyperintense on T2-weighted images. CHEST  , e133-e138DOI: ( /j.chest ) Copyright © 2017 American College of Chest Physicians Terms and Conditions

6 Figure 5 The cut surface was white and semitranslucent with a gelatinous appearance, completely surrounded by a thin fibrous capsule. CHEST  , e133-e138DOI: ( /j.chest ) Copyright © 2017 American College of Chest Physicians Terms and Conditions

7 Figure 6 Monomorphic collagenous stroma between bland spindle cells with areas of myxoid background. Characteristic mature ganglion cells with ample granular cytoplasm and round smooth nuclei are seen in small groups. Hematoxylin-eosin stain. CHEST  , e133-e138DOI: ( /j.chest ) Copyright © 2017 American College of Chest Physicians Terms and Conditions

8 Figure 7 The stroma was positive for S-100 immunoperoxidase stain, and the singly distributed cells were strongly positive for neurofilament immunoperoxidase stain. CHEST  , e133-e138DOI: ( /j.chest ) Copyright © 2017 American College of Chest Physicians Terms and Conditions


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