1. Figure 3 Selective autophagy related to liver metabolism
Figure 3 | Selective autophagy related to liver metabolism. a | Parkin-mediated mitophagy. b | Pexophagy. c | Lipophagy. d | Glycophagy. e | SQSTM1-mediated degradation of KEAP1. DFCP1, zinc finger FYVE domain-containing protein 1; E3, E3 ubiquitin ligase; GL1, gamma-aminobutyric acid receptor-associated protein-like 1 (also known as GABARAPL1); KEAP1, kelch-like ECH-associated protein 1; LC3, microtubule-associated proteins 1A/1B light chain 3; NBR1, Next to BRCA1 gene protein 1; NDP52, calcium-binding and coiled-coil domain-containing protein 2; NRF2, nuclear factor erythroid 2-related factor 2; OPTN, optineurin; Parkin, E3 ubiquitin-protein ligase parkin; PEX2, peroxisome biogenesis factor 2; PEX5, peroxisomal targeting signal 1 receptor; PEX10, peroxisome biogenesis factor 10; PEX12, peroxisome assembly protein 12; PLINs, Pelilipins; SESN2, sestrin 2; sMAF, small MAF family proteins; SQSTM1, sequestosome 1; STBD1, Starch-binding domain-containing protein 1; UB, ubiquitin; WIPI, WIPWD repeat domain phosphoinositide-interacting protein.
Ueno, T. & Komatsu, M. (2017) Autophagy in the liver: functions in health and disease
Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro