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Quorum-sensing activity and related virulence factor expression in clinically pathogenic isolates of Pseudomonas aeruginosa  R. Le Berre, S. Nguyen, E.

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Presentation on theme: "Quorum-sensing activity and related virulence factor expression in clinically pathogenic isolates of Pseudomonas aeruginosa  R. Le Berre, S. Nguyen, E."— Presentation transcript:

1 Quorum-sensing activity and related virulence factor expression in clinically pathogenic isolates of Pseudomonas aeruginosa  R. Le Berre, S. Nguyen, E. Nowak, E. Kipnis, M. Pierre, F. Ader, R. Courcol, B.P. Guery, K. Faure  Clinical Microbiology and Infection  Volume 14, Issue 4, Pages (April 2008) DOI: /j x Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

2 Fig. 1 Box-plot of the production levels of quorum-sensing-related virulence factors in culture supernatants from 56 non-clonal clinically pathogenic isolates of Pseudomonas aeruginosa and comparison with laboratory reference strains PAO1 and PA103. Logarithmic scales are used. Dotted lines show the relative levels of production of reference strains PAO1 and PA103. (a) Elastase production as assessed by elastin Congo red assay, expressed as OD495/OD600. (b) Pyocyanin production as assessed by absorbance in an acidic solution expressed as OD520/OD600. Clinical Microbiology and Infection  , DOI: ( /j x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

3 Fig. 2 Production of autoinducers (a) N-3-oxododecanoyl-L-homoserine lactone (C12-HSL) and (b) N-butanoyl-L-homoserine lactone (C4-HSL) in culture supernatants from 56 non-clonal clinically pathogenic isolates of Pseudomonas aeruginosa and comparison with laboratory reference strains PAO1 and PA103. Results are expressed in μmol/L on logarithmic scales. Clinical Microbiology and Infection  , DOI: ( /j x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions


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