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Postpartum haemorrhage related early increase in D-dimers is inhibited by tranexamic acid: haemostasis parameters of a randomized controlled open labelled.

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Presentation on theme: "Postpartum haemorrhage related early increase in D-dimers is inhibited by tranexamic acid: haemostasis parameters of a randomized controlled open labelled."— Presentation transcript:

1 Postpartum haemorrhage related early increase in D-dimers is inhibited by tranexamic acid: haemostasis parameters of a randomized controlled open labelled trial  A.S. Ducloy-Bouthors, A Duhamel, E Kipnis, A Tournoys, A Prado-Dupont, A Elkalioubie, E Jeanpierre, G Debize, E Peynaud-Debayle, D DeProst, C Huissoud, A Rauch, S Susen  British Journal of Anaesthesia  Volume 116, Issue 5, Pages (May 2016) DOI: /bja/aew021 Copyright © 2016 The Author(s) Terms and Conditions

2 Fig. 1 Biological parameters collected at baseline. Comparison with reference non haemorrhagic women. Bleeding women (green circle: H untreated haemorrhagic group) and non-bleeding women (blue circle: NH non haemorrhagic group). Data expressed as median [interquartile range]. †P values for H vs NH using Mann-Whitney U-test non parametric test. (a) D Dimers (ng ml−1) (b) Fibrinogen (g litre−1) (c) Factor II (IU ml−1). British Journal of Anaesthesia  , DOI: ( /bja/aew021) Copyright © 2016 The Author(s) Terms and Conditions

3 Fig. 2 Haemostasis parameters in treated TA vs untreated haemorrhagic H groups. Haemostasis parameters collected at onset of PPH, 30 min, 2 and 6 h in treated tranexamic haemorrhagic group (open triangle ▵) compared with untreated H haemorrhagic group (open circle ○): Data expressed as median [interquartile range]. ††P values for non-haemorrhagic group vs untreated haemorrhagic group by using Mann-Whitney U-test non parametric test. (a) D Dimers (ng ml−1) (b): Plasmin antiplasmin PAP complexes (ng ml−1) (c): Fibrinogen (g litre−1) (d): Factor II (IU ml−1). British Journal of Anaesthesia  , DOI: ( /bja/aew021) Copyright © 2016 The Author(s) Terms and Conditions


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