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Volume 154, Issue 5, Pages e3 (April 2018)

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1 Volume 154, Issue 5, Pages 1273-1281.e3 (April 2018)
Determining Risk of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on Epidemiologic Factors and Genetic Variants  Jing Dong, Matthew F. Buas, Puya Gharahkhani, Bradley J. Kendall, Lynn Onstad, Shanshan Zhao, Lesley A. Anderson, Anna H. Wu, Weimin Ye, Nigel C. Bird, Leslie Bernstein, Wong-Ho Chow, Marilie D. Gammon, Geoffrey Liu, Carlos Caldas, Paul D. Pharoah, Harvey A. Risch, Prasad G. Iyer, Brian J. Reid, Laura J. Hardie, Jesper Lagergren, Nicholas J. Shaheen, Douglas A. Corley, Rebecca C. Fitzgerald, David C. Whiteman, Thomas L. Vaughan, Aaron P. Thrift  Gastroenterology  Volume 154, Issue 5, Pages e3 (April 2018) DOI: /j.gastro Copyright © 2018 AGA Institute Terms and Conditions

2 Figure 1 The receiver operating characteristic curves associated with risk prediction models for (A) BE and (B) EAC. Demographic/lifestyle model includes age, sex, smoking, BMI, and use of NSAIDs. Gastroenterology  , e3DOI: ( /j.gastro ) Copyright © 2018 AGA Institute Terms and Conditions

3 Supplementary Figure 1 Distributions of the PRS in the BEACON and UK datasets (cases and controls). Gastroenterology  , e3DOI: ( /j.gastro ) Copyright © 2018 AGA Institute Terms and Conditions

4 Supplementary Figure 2 Box-plots of the PRS separately in cases (BE and EAC) and controls. Gastroenterology  , e3DOI: ( /j.gastro ) Copyright © 2018 AGA Institute Terms and Conditions


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