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DNA
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What is DNA? Contains all genetic information of the entire organism
Located in the nucleus of all cells (with a few exceptions!) mature red blood cells have no nucleus sex cells have half the amount of genetic information (haploid) A “full set” in humans is 46 chromosomes Made up of 23 pairs (diploid)
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But not in all animals! Organism # of Chromosome Pairs Human 23
Drosophila (fruit fly) 4 E.coli (bacteria) Mosquito 3 Fly Frog 18 Cat 19 Chimpanzee 24 Horse 32 Dog 39 Onion 8 Peanut 12
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DNA spends most of its time in a long string called chromatin
During cell division, chromatin coils up tightly to form chromosomes
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the section of DNA that codes for a protein is called a gene
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DNA -> RNA -> Protein (made of amino acid)
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DNA Structure DNA is made of nucleotides composed of 3 parts DNA:
5 carbon sugar: deoxyribose one nitrogenous base (4 possible options!) phosphate group DNA: Deoxyribo- Nucleic acid
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There are two types of nitrogenous bases:
1. Purines -Adenine (A) and Guanine (G) -2 fused rings 2. Pyrimidines -Cytosine (C) and Thymine (T) -only one ring Adenine ALWAYS bonds with thymine Guanine ALWAYS bonds with cytosine -this is called complimentary base pairing
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DNA looks like a twisted ladder
This arrangement is called a double helix
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Alternating sugar and phosphates make up the backbone (the “rails” of the ladder)
Bases make up the “rungs” and are held together by weak hydrogen bonds
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