1. Volume 21, Issue 2, Pages 318-323 (February 2013)
Minimizing the Inhibitory Effect of Neutralizing Antibody for Efficient Gene Expression in the Liver With Adeno-associated Virus 8 Vectors 
Jun Mimuro, Hiroaki Mizukami, Shuji Hishikawa, Tomokazu Ikemoto, Akira Ishiwata, Asuka Sakata, Tsukasa Ohmori, Seiji Madoiwa, Fumiko Ono, Keiya Ozawa, Yoichi Sakata 
Molecular Therapy 
Volume 21, Issue 2, Pages (February 2013)
DOI: /mt
Copyright © 2013 The American Society of Gene & Cell Therapy Terms and Conditions

2. Figure 1
Expression of FIX T262A in macaques after direct vector injection into portal veins. Macaques (n = 3) were subjected to direct injection of AAV8 vector into the portal vein. Concentrations of FIX T262A in macaque plasma samples (macaque #26, open triangles; #27, open circles; #29, closed squares) were measured by ELISA. AAV, adeno-associated virus; ELISA, enzyme-linked immunosorbent assay; FIX, factor IX.
Molecular Therapy  , DOI: ( /mt )
Copyright © 2013 The American Society of Gene & Cell Therapy Terms and Conditions

3. Figure 2
Fluorography in macaque #37. A balloon catheter was inserted into the portal vein of macaque #37 and contrast medium injected before vector administration. The left portal vein branches can be visualized. The arrow (white) indicates the tip of the catheter. See Supplementary Video S1 which also recorded inflation of the balloon before the vector administration and deflation of the balloon after the administration.
Molecular Therapy  , DOI: ( /mt )
Copyright © 2013 The American Society of Gene & Cell Therapy Terms and Conditions

4. Figure 3
Expression of FIX T262A in macaques following balloon catheter-guided vector injection into portal veins. Three macaques (n = 3) were subjected to balloon catheter-guided vector injection into the portal vein. Concentrations of FIX T262A in macaque plasma samples (#37, closed circles; #38, open squares; #42, closed triangles) were measured by ELISA. ELISA, enzyme-linked immunosorbent assay; FIX, factor IX.
Molecular Therapy  , DOI: ( /mt )
Copyright © 2013 The American Society of Gene & Cell Therapy Terms and Conditions