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Detecting Glaucoma Progression Using Guided Progression Analysis with OCT and Visual Field Assessment in Eyes Classified by International Classification.

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Presentation on theme: "Detecting Glaucoma Progression Using Guided Progression Analysis with OCT and Visual Field Assessment in Eyes Classified by International Classification."— Presentation transcript:

1 Detecting Glaucoma Progression Using Guided Progression Analysis with OCT and Visual Field Assessment in Eyes Classified by International Classification of Disease Severity Codes  Alexander T. Nguyen, MD, David S. Greenfield, MD, Amitabha S. Bhakta, PhD, Jennifer Lee, MD, William J. Feuer, MS  Ophthalmology Glaucoma  Volume 2, Issue 1, Pages (January 2019) DOI: /j.ogla Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

2 Figure 1 Histogram illustrating a comparison of glaucoma progression events identified using OCT retinal nerve fiber layer (RNFL) and ganglion cell–inner plexiform layer (GCIPL) analysis and visual field (VF) testing in eyes with mild (n = 62), moderate (n = 39), and severe (n = 46) glaucoma. Ophthalmology Glaucoma 2019 2, 36-46DOI: ( /j.ogla ) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

3 Figure 2 Venn diagram showing glaucoma progression detection using OCT retinal nerve fiber layer (RNFL) and ganglion cell–inner plexiform layer (GCIPL) analysis and visual field (VF) testing among the study population (n = 147). Ophthalmology Glaucoma 2019 2, 36-46DOI: ( /j.ogla ) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

4 Figure 3 OCT Guided Progression Analysis (GPA) of retinal nerve fiber layer (RNFL) and ganglion cell–inner plexiform layer (GCIPL) thickness and visual field (VF) testing of the left eye of a patient with severe glaucoma illustrating glaucoma progression. On the right is a panomap consisting of combined RNFL and macular GCIPL deviation maps obtained at the baseline and final visit. The asterisks identify locations of progression highlighted on the spectral-domain OCT GPA images. PD = pattern deviation. Ophthalmology Glaucoma 2019 2, 36-46DOI: ( /j.ogla ) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

5 Figure 4 Scatterplots demonstrating the relationship between the rate of visual field mean deviation (MD) loss and (A) OCT retinal nerve fiber layer (RNFL) loss in eyes with RNFL progression and (B) the rate of OCT ganglion cell–inner plexiform layer (GCIPL) loss in eyes with GCIPL progression. Ophthalmology Glaucoma 2019 2, 36-46DOI: ( /j.ogla ) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

6 Figure 5 Kaplan-Meier plot presenting the cumulative progression rates detected by OCT retinal nerve fiber layer (RNFL) and ganglion cell–inner plexiform layer (GCIPL) analysis and visual field (VF) testing in all eyes of all patients (n = 147). OCT detected significantly more progression events than VF testing (P < 0.001, McNemar’s test). Ophthalmology Glaucoma 2019 2, 36-46DOI: ( /j.ogla ) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions


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