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Genetic variation in TH17 pathway genes, childhood asthma, and total serum IgE levels  Maximilian Schieck, MSc, Sven Michel, MSc, Kathrin Suttner, PhD,

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Presentation on theme: "Genetic variation in TH17 pathway genes, childhood asthma, and total serum IgE levels  Maximilian Schieck, MSc, Sven Michel, MSc, Kathrin Suttner, PhD,"— Presentation transcript:

1 Genetic variation in TH17 pathway genes, childhood asthma, and total serum IgE levels 
Maximilian Schieck, MSc, Sven Michel, MSc, Kathrin Suttner, PhD, Thomas Illig, PhD, Sonja Zeilinger, MSc, Andre Franke, MD, Christian Vogelberg, MD, Andrea von Berg, MD, Albrecht Bufe, MD, Andrea Heinzmann, MD, Otto Laub, MD, Ernst Rietschel, MD, Burkhard Simma, MD, Thomas Frischer, MD, Jon Genuneit, MD, Sebastian Kerzel, MD, Michael Kabesch, MD  Journal of Allergy and Clinical Immunology  Volume 133, Issue 3, Pages (March 2014) DOI: /j.jaci Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Genes associated with the TH17 pathway. The PubMed database was reviewed for molecules involved in the differentiation of naive CD4+ T cells into the TH17 lineage or maintenance of the TH17 phenotype (A), key transcription factors (B), and TH17 effector cytokines (C). All 17 genes were selected for genetic association analyses with asthma phenotypes and total serum IgE levels. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig E1 Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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