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Micro-CT quantification of subchondral endplate changes in intervertebral disc degeneration  J.P.H.J. Rutges, O.P. Jagt van der, F.C. Oner, A.J. Verbout,

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Presentation on theme: "Micro-CT quantification of subchondral endplate changes in intervertebral disc degeneration  J.P.H.J. Rutges, O.P. Jagt van der, F.C. Oner, A.J. Verbout,"— Presentation transcript:

1 Micro-CT quantification of subchondral endplate changes in intervertebral disc degeneration 
J.P.H.J. Rutges, O.P. Jagt van der, F.C. Oner, A.J. Verbout, R.J.M. Castelein, J.A. Kummer, H. Weinans, L.B. Creemers, W.J.A. Dhert  Osteoarthritis and Cartilage  Volume 19, Issue 1, Pages (January 2011) DOI: /j.joca Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Example of macroscopical appearance and micro-CT images of IVDs for each degeneration grade according to the Thompson score. Osteoarthritis and Cartilage  , 89-95DOI: ( /j.joca ) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 Schematic overview of study procedure: micro-CT, VOI selection, and segmentation. Osteoarthritis and Cartilage  , 89-95DOI: ( /j.joca ) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

4 Fig. 3 A: Bone volume fraction for endplate and vertebral VOIs for each degeneration grade. B: Difference in bone volume fraction between endplate and vertebral VOIs for each degeneration grade. Grade II, III and V IVDs showed a significantly higher BV/TV in the endplate VOIs compared to the grade I VOIs. Error bars represent 95% confidence intervals. Grade I: N=5, II: N=5, III: N=7, IV: N=6 and grade V: N=4. ∗P<0.05. Osteoarthritis and Cartilage  , 89-95DOI: ( /j.joca ) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions


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