1. Regulation of intestinal nuclear factor-κB activity and E-selectin expression during sepsis: A role for peroxynitrite 
Cameron W. Lush, Gediminas Cepinskas, Peter R. Kvietys 
Gastroenterology 
Volume 124, Issue 1, Pages (January 2003)
DOI: /gast
Copyright © 2003 American Gastroenterological Association Terms and Conditions

2. Fig. 1
NF-κB in nuclear extracts obtained from the small intestine of wild-type and iNOS−/− mice 3 hours after administration of LPS (5 μg IP). A representative experiment (EMSA) is shown in B, and quantitative results (densitometry) of 4 experiments are shown in A.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions

3. Fig. 2
NF-κB in nuclear extracts obtained from the small intestine of wild-type and Cu/Zn-SOD transgenic mice 3 hours after administration of LPS (5 μg IP). A representative experiment (EMSA) is shown in B, and quantitative results (densitometry) of 4 experiments are shown in A.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions

4. Fig. 3
Effects of pretreatment of wild-type mice with the ONOO− decomposition catalyst FeTPPS (10 mg/kg body wt IP) on the subsequent accumulation of NF-κB in nuclear extracts obtained from the small intestine 3 hours after administration of LPS (5 μg IP). A representative experiment (EMSA) is shown in B, and quantitative results (densitometry) of 4 experiments are shown in A.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions

5. Fig. 4
E-selectin expression in (A) small intestine, (B) large intestine, (C) heart, and (D) lungs 3 hours after LPS challenge (5 μg IP) in wild-type and iNOS−/− mice. Values are mean ± SE (n = 5 in each group). *P < 0.05 vs. control; †P < 0.05 between LPS wild-type and LPS iNOS−/− mice.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions

6. Fig. 5
E-selectin expression in (A) small intestine, (B) large intestine, (C) heart, and (D) lungs 3 hours after LPS challenge (5 μg IP) in wild-type, Cu/Zn-SOD transgenic, and wild-type mice pretreated with the SOD mimetic MnTBAP (10 mg/kg body wt IP). Values are mean ± SE (n = 5 in each group). *P < 0.05 vs. control.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions

7. Fig. 6
Effects of pretreatment of wild-type mice with the ONOO− decomposition catalyst FeTPPS (10 mg/kg body wt IP) on E-selectin expression in (A) small intestine, (B) large intestine, (C) heart, and (D) lungs 3 hours after LPS challenge (5 μg IP). Values are mean ± SE (n = 5 in each group). *P < 0.05 vs. control; †P < 0.05 between LPS-stimulated wild-type and LPS-stimulated FeTPPS-pretreated wild-type mice.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions

8. Fig. 7
Effects of the ONOO− decomposition catalyst FeTPPS (10 mg/kg body wt IP) on nitrotyrosine staining in the heart, lung, and small intestine. Staining for nitrotyrosine is brown.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions

9. Fig. 8
(A) Effects of pretreatment of cultured HUVEC with FeTPPS on the subsequent LPS-induced NF-κB activity. A representative experiment (EMSA) is shown in the lower panel, and quantitative results (densitometry) of 3 experiments are shown in the upper panel. (B) Effects of pretreatment of HUVEC with either FeTMPyP (25 or 50 μmol/L) or ZnTMPyP (25 or 50 μmol/L) on subsequent LPS-induced NF-κB accumulation in the nucleus. A representative experiment (EMSA) is shown in the lower panel, and quantitative results (densitometry) of 3 experiments are shown in the upper panel. (C) Effects of pretreatment of HUVEC with FeTPPS on the subsequent LPS-induced surface level expression of E-selectin. Values are mean ± SE (n = 3). *P < 0.05 vs. control.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions