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Updates in the Management of Acute Lung Injury: A Focus on the Overlap Between AKI and ARDS
Eric J. Seeley Advances in Chronic Kidney Disease Volume 20, Issue 1, Pages (January 2013) DOI: /j.ackd Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions
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Figure 1 Patients with ARDS and severe AKI have a dramatic increase in mortality. Reproduced with permission from Cooke et al.3 Advances in Chronic Kidney Disease , 14-20DOI: ( /j.ackd ) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions
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Figure 2 The incidence and effect of AKI in patients with ARDS is likely underestimated because of aggressive volume resuscitation. Reassignment from AKI absent to AKI present identifies a group of patients with increased hospital mortality. Reproduced and adapted with permission from Liu et al.14 Advances in Chronic Kidney Disease , 14-20DOI: ( /j.ackd ) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions
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Figure 3 Interactions between the injured lung and injured kidney during critical illness can lead to an inflammatory loop that worsens kidney injury and increases pulmonary vascular permeability. PMN, polymorphonuclear leukocyte. Advances in Chronic Kidney Disease , 14-20DOI: ( /j.ackd ) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions
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Figure 4 Patients randomized to the conservative fluid therapy arm of the FACTT study were net fluid even by the end of the 7-d trial compared with those in the liberal arm, who were approximately 7 L positive. Fluid administered to the liberal group was comparable to standard practice on the basis of two previous ARDSnet trials—the ARMA and ALVEOLI trials. Reproduced with permission from Wiedemann et al.22 Advances in Chronic Kidney Disease , 14-20DOI: ( /j.ackd ) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions
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