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Xenon has no effect on cytokine balance and adhesion molecule expression within an isolated cardiopulmonary bypass system†‡  A. Bedi, W.T. McBride, M.A.

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Presentation on theme: "Xenon has no effect on cytokine balance and adhesion molecule expression within an isolated cardiopulmonary bypass system†‡  A. Bedi, W.T. McBride, M.A."— Presentation transcript:

1 Xenon has no effect on cytokine balance and adhesion molecule expression within an isolated cardiopulmonary bypass system†‡  A. Bedi, W.T. McBride, M.A. Armstrong, J.M. Murray, J.P.H. Fee  British Journal of Anaesthesia  Volume 89, Issue 4, Pages (October 2002) DOI: /bja/aef232 Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

2 Fig 1 The mean channel fluorescence (MCF), expressed as linear units, of monocyte HLA-Dr, CD18, CD11b and l-selectin in donor blood at baseline (time 0) and after 30, 60 and 90 min of isolated CPB with xenon in oxygen, and with oxygen-enriched air (control). The error bars represent 1 sd. British Journal of Anaesthesia  , DOI: ( /bja/aef232) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

3 Fig 2 The mean channel fluorescence (MCF), expressed as linear units, of granulocyte HLA-Dr, CD18, CD11b and l-selectin in donor blood at baseline (time 0) and after 30, 60 and 90 min of isolated CPB with xenon in oxygen, and with oxygen-enriched air (control). The error bars represent 1 sd. British Journal of Anaesthesia  , DOI: ( /bja/aef232) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

4 Fig 3 The mean channel fluorescence (MCF), expressed as linear units, of lymphocyte HLA-Dr, CD18, CD11b and l-selectin in donor blood at baseline (time 0) and after 30, 60 and 90 min of isolated CPBwith xenon in oxygen, and with oxygen-enriched air (control). The error bars represent 1 sd. Significant differences from time 0: **P<0.01; ***P<0.001. British Journal of Anaesthesia  , DOI: ( /bja/aef232) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

5 Fig 4 Plasma IL-8, TNF-sr-2, and IL-10 levels (pg ml−1) at baseline (time 0) and after 30, 60 and 90 min of isolated CPB with xenon in oxygen, and with oxygen-enriched air (control). The error bars represent 1 sd. Significant differences from time 0: *P<0.05; **P<0.01; ***P<0.001. British Journal of Anaesthesia  , DOI: ( /bja/aef232) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

6 Fig 5 Plasma IL-1ra, Il-1β, and TNFα levels (pg ml−1) at baseline (time 0) and after 30, 60 and 90 min of isolated CPB with xenon in oxygen and with oxygen-enriched air (control). The error bars represent 1 sd. British Journal of Anaesthesia  , DOI: ( /bja/aef232) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions


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