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Volume 7, Issue 1, Pages 53-61 (April 2000)
Induction of c-fos and interleukin-2 genes expression in the central nervous system following stressor stimuli T.B. Kazakova, S.V. Barabanova, N.S. Novikova, M.A. Nosov, V. Rogers, E.A. Korneva Pathophysiology Volume 7, Issue 1, Pages (April 2000) DOI: /S (00)
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Fig. 1 Photomicrographs illustrated the localization of c-fos mRNA in the dorsal horns of the spinal cord. Sections were taken from animals injected with 5% mustard in vegetable oil. (a) c-fos mRNA-intact animal, (b) c-fos mRNA-stimulated animal. Pathophysiology 2000 7, 53-61DOI: ( /S (00) )
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Fig. 2 Photomicrographs illustrated the localization of c-fos mRNA and IL-2 m RNA in the lateral hypothalamic area. Sections were taken from animals injected with 5% mustard in vegetable oil 2 h after the injection. Expression of: (a) c-fos mRNA-intact animal; (b) c-fos mRNA stimulated animal; (c) IL-2 mRNA-intact animal; (d) IL-2 mRNA-stimulated animal. Pathophysiology 2000 7, 53-61DOI: ( /S (00) )
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Fig. 2 Photomicrographs illustrated the localization of c-fos mRNA and IL-2 m RNA in the lateral hypothalamic area. Sections were taken from animals injected with 5% mustard in vegetable oil 2 h after the injection. Expression of: (a) c-fos mRNA-intact animal; (b) c-fos mRNA stimulated animal; (c) IL-2 mRNA-intact animal; (d) IL-2 mRNA-stimulated animal. Pathophysiology 2000 7, 53-61DOI: ( /S (00) )
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Fig. 2 Photomicrographs illustrated the localization of c-fos mRNA and IL-2 m RNA in the lateral hypothalamic area. Sections were taken from animals injected with 5% mustard in vegetable oil 2 h after the injection. Expression of: (a) c-fos mRNA-intact animal; (b) c-fos mRNA stimulated animal; (c) IL-2 mRNA-intact animal; (d) IL-2 mRNA-stimulated animal. Pathophysiology 2000 7, 53-61DOI: ( /S (00) )
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Fig. 2 Photomicrographs illustrated the localization of c-fos mRNA and IL-2 m RNA in the lateral hypothalamic area. Sections were taken from animals injected with 5% mustard in vegetable oil 2 h after the injection. Expression of: (a) c-fos mRNA-intact animal; (b) c-fos mRNA stimulated animal; (c) IL-2 mRNA-intact animal; (d) IL-2 mRNA-stimulated animal. Pathophysiology 2000 7, 53-61DOI: ( /S (00) )
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Fig. 3 Distribution of c-fos mRNA and IL-2 mRNA in the different brain structures. The Swanson's stereotaxic rat brain atlas was used for the drawings (the layer N 26). Drawings illustrate the distribution of c-fos mRNA and IL-2 mRNA in the brain 2 h after 5% mustard in vegetable oil injection: (A) c-fos mRNA-intact animals; (B) c-fos mRNA-stimulated animals; (C) IL-2 mRNA-intact animals; (D) IL-2 mRNA-stimulated animals. In a frame on the scheme the average amount of labeled cells shows distribution of c-fos mRNA or IL-2 mRNA in different layers of the sensori-motor zone of the brain cortex. Pathophysiology 2000 7, 53-61DOI: ( /S (00) )
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Fig. 4 Distribution of the Dig-IL-2 mRNA in different cells in the different parts of the brain after 5% mustard in vegetable oil injection. The arrows indicate: (a) unlabeled cells, (b) label in the nucleus, (c) label in the peripheria of the nucleus. The data demonstrated IL-2 mRNA transport from the nuclei to the cytoplasma. Pathophysiology 2000 7, 53-61DOI: ( /S (00) )
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