1. Hypotension After Cardiac Operations Based on Autoregulation Monitoring Leads to Brain Cellular Injury 
Daijiro Hori, MD, Masahiro Ono, MD, PhD, Thomas E. Rappold, BS, John V. Conte, MD, Ashish S. Shah, MD, Duke E. Cameron, MD, Hideo Adachi, MD, PhD, Allen D. Everett, MD, Charles W. Hogue, MD 
The Annals of Thoracic Surgery 
Volume 100, Issue 2, Pages (August 2015)
DOI: /j.athoracsur
Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

2. Fig 1
Cerebral oximetry index (COx) results obtained during cardiopulmonary bypass placed in 5 mm Hg bins. Optimal mean arterial pressure (MAP) was defined as that MAP with the lowest COx. As MAP moves away from the optimal MAP, COx increases, indicating trends towards pressure-dependent changes in cerebral blood flow. In this example, the optimal MAP is 80 mm Hg (black arrow). The range bars indicate the standard deviation.
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

3. Fig 2
Box-and-whisker plot comparing plasma glial fibrillary acidic protein (GFAP) levels on postoperative day 1 for patients who had an average mean arterial pressure (MAP) in the intensive care unit (ICU) above the optimal MAP and patients who had an average MAP in the ICU below the optimal MAP (p < 0.001). The horizontal line in the shaded box represents the median value, the top and bottom of the shaded box represent the interquartile range, and the whiskers below and above represent ±1.5 × the interquartile range; points beyond the whiskers are outliers.
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

4. Fig 3
Box-and-whisker plot comparing the product of magnitude and duration of mean arterial pressure (MAP) below the optimal MAP (area under the curve < OptMAP) in patients who had average MAP in the intensive care unit (ICU) above the optimal MAP and for patients who had average MAP (ICU) below the MAP (p < 0.001). The horizontal line in the shaded box represents the median value, the top and bottom of the shaded box represent the interquartile range, and the whiskers below and above the shaded area represent ±1.5 × the interquartile range; points beyond the whiskers are outliers.
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

5. Fig 4
Spearman correlation ratio between plasma glial fibrillary acidic protein levels on postoperative day 1 (POD1) and the product of magnitude and duration of blood pressure below the area under the curve (AUC) of the optimal mean arterial pressure (r = 0.31, p < 0.001).
The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )
Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions