3. Disease Burden of VTE

4. Phases of VTE Treatment

5. Designs of Phase 3 Acute VTE Trials

6. Risk for Recurrent VTE After Diagnosis

7. Acute VTE Treatment Trials

8. Heparin Bridge in NOAC VTE Trials Rationale for Differences in Trial Design?

9. Prognostic Assessment of Patients With Acute PE

10. Acute PE Based on Early (Intermediate) Mortality Risk

11. ESC 2014 PE Anticoagulation Recommendations

12. NOACs VTE Acute Treatment Trials

13. Approaches to Managing DVT vs PEa

14. NOACs in Frail and Elderly Patients

15. Management of VTE in Cancer Patients

16. Anticoagulant Treatment of VTE Risk-benefit of NOAC vs VKA

17. NOACs VTE Extended Treatment Trials

18. Take-Home Messages

19. Abbreviations

20. Abbreviations (cont)

21. References

22. References (cont)

23. References (cont)