1. Supplemental Figure 1
Patient 2

2. Supplemental Figure 2 Patient: 1 2 3 Patient: 4 5 6 No cDNA No cDNA
IgA
IgG
-Ac
IgA
IgG
-Ac
IgA
IgG
-Ac
IgA
IgG
-Ac
IgA
IgG
-Ac
IgA
IgG
-Ac
Patient: 4 5 6
No cDNA
IgA
IgG
-Ac
IgA
IgG
-Ac
IgA
IgG
-Ac
IgA
IgG
-Ac

3. Supplemental Figure 3 Patient 1 Patient 4 No cDNA IgA Patient 1
-Ac
-Ac
-Ac
IGHV 1 2 3 4 5 6 7 1 2 3 4 5 6 7 1 2 3 4 5 6 7
IgA
IGHV 1 2 3 4 5 6 7
Patient 1
Patient 4
No cDNA
IgG

4. Supplemental Figure 4 Patient 1 2 3 1 2 3 IgM -Ac Patient 4 5 6
No cDNA
No cDNA
Patient 1 2 3 1 2 3
IgM
-Ac No
cDNA
Patient 4 5 6
IgM
-Ac
IgM
-Ac
IgM
-Ac
IgM
-Ac