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The association between histological, macroscopic and magnetic resonance imaging assessed synovitis in end-stage knee osteoarthritis: a cross-sectional.

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Presentation on theme: "The association between histological, macroscopic and magnetic resonance imaging assessed synovitis in end-stage knee osteoarthritis: a cross-sectional."— Presentation transcript:

1 The association between histological, macroscopic and magnetic resonance imaging assessed synovitis in end-stage knee osteoarthritis: a cross-sectional study  R.G.C. Riis, H. Gudbergsen, O. Simonsen, M. Henriksen, N. Al-Mashkur, M. Eld, K.K. Petersen, O. Kubassova, A.C. Bay Jensen, J. Damm, H. Bliddal, L. Arendt-Nielsen, M. Boesen  Osteoarthritis and Cartilage  Volume 25, Issue 2, Pages (February 2017) DOI: /j.joca Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 DCE-MRI analysis. A: Heuristic TIC from a point of interest in the popliteal artery (x-axis: time (s); y-axis: relative signal intensity (baseline = 1.0)). IRW: initial rate of washout; AUC: area under the curve; Tonset: time (in seconds) to onset of contrast-enhancement; Twashout: time (in seconds) to washout of contrast. B: Assignment and colour-coding of the voxels within the ROI drawn around the synovium in the suprapatellar recess based on the shape of the TIC (no colour = no enhancement). Plateau (green) and washout (red) represent the most perfused patterns/voxels. C–F: Parametric maps. Brighter colours indicate higher values. ROI drawn around the synovium in the suprapatellar recess (C: no map; D: IRE map; E: ME map; F: Ktrans map). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 Assessing histological synovitis according to Krenn et al.
Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

4 Fig. 3 Trial profile. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions


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