1. Individualizing Therapy for RA: Are We There Yet?

3. Introduction

4. Molecular Pathways in RA

5. Identifying Biomarkers of Response

6. Biomarker Challenges and Opportunities

7. RF vs ACPAs

8. PAD4 and PAD4 Autoantibodies

10. PAD4 Autoantibodies and Response

11. Educating Patients

12. Prognostic Value of ACPA Positivity

13. PAD4 Autoantibodies and Radiography

14. Other Prognostic Factors

15. Smoking and ACPA

16. Return to Clinical Case: Managing Our Patient

17. AMPLE Trial: ACPA and Response

18. Corrona Registry Study

19. Seropositive Status and B-Cell Depletion

20. Return to Clinical Case: Shared Decision-Making

21. Take-Home Points

22. Abbreviations