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Painful Ophthalmoplegia (Tolosa-Hunt Variant): Autopsy Findings in a Patient With Necrotizing Intracavernous Carotid Vasculitis and Inflammatory Disease.

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Presentation on theme: "Painful Ophthalmoplegia (Tolosa-Hunt Variant): Autopsy Findings in a Patient With Necrotizing Intracavernous Carotid Vasculitis and Inflammatory Disease."— Presentation transcript:

1 Painful Ophthalmoplegia (Tolosa-Hunt Variant): Autopsy Findings in a Patient With Necrotizing Intracavernous Carotid Vasculitis and Inflammatory Disease of the Orbit  R. JEAN CAMPBELL, M.B., Ch.B.  Mayo Clinic Proceedings  Volume 62, Issue 6, Pages (June 1987) DOI: /S (12) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Fig. 1 Base of skull, showing hemorrhagic discoloration of roof of right orbit. Mayo Clinic Proceedings  , DOI: ( /S (12) ) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Fig. 2 Specimen obtained from en bloc dissection of dorsum sellae together with pituitary and cavernous sinus. Note distended cavernous sinus on right and intramural thrombus within carotid artery. Mayo Clinic Proceedings  , DOI: ( /S (12) ) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

4 Fig. 3 Photomicrographs of specimen shown in Figure 2. A, Wall of cavernous sinus shows mural clot (at left) and inflammatory tissue within adjacent bone (at right). (Hematoxylin and eosin; x40.) B, Granulation tissue in wall of right cavernous sinus. Mononuclear cells, new vessels, and fibroblasts are interspersed. (Hematoxylin and eosin; x400.) Mayo Clinic Proceedings  , DOI: ( /S (12) ) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions

5 Fig. 4 Postmortem angiogram, showing rupture of intracranial portion of right internal carotid artery. Mayo Clinic Proceedings  , DOI: ( /S (12) ) Copyright © 1987 Mayo Foundation for Medical Education and Research Terms and Conditions


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