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Factors Associated With Progression of Barrett’s Esophagus: A Systematic Review and Meta-analysis  Rajesh Krishnamoorthi, Siddharth Singh, Karthik Ragunathan,

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Presentation on theme: "Factors Associated With Progression of Barrett’s Esophagus: A Systematic Review and Meta-analysis  Rajesh Krishnamoorthi, Siddharth Singh, Karthik Ragunathan,"— Presentation transcript:

1 Factors Associated With Progression of Barrett’s Esophagus: A Systematic Review and Meta-analysis 
Rajesh Krishnamoorthi, Siddharth Singh, Karthik Ragunathan, Kavel Visrodia, Kenneth K. Wang, David A. Katzka, Prasad G. Iyer  Clinical Gastroenterology and Hepatology  Volume 16, Issue 7, Pages e8 (July 2018) DOI: /j.cgh Copyright © 2018 AGA Institute Terms and Conditions

2 Figure 1 Flow sheet summarizing study identification and selection.
Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

3 Figure 2 Forest plots. Predictors of progression to HGD/EAC.
Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

4 Supplementary Figure 1 Summary forest plot: comparison of pooled odds ratios of predictors of progression. CI, confidence interval. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

5 Supplementary Figure 1 Summary forest plot: comparison of pooled odds ratios of predictors of progression. CI, confidence interval. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

6 Supplementary Figure 1 Summary forest plot: comparison of pooled odds ratios of predictors of progression. CI, confidence interval. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

7 Supplementary Figure 1 Summary forest plot: comparison of pooled odds ratios of predictors of progression. CI, confidence interval. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

8 Supplementary Figure 1 Summary forest plot: comparison of pooled odds ratios of predictors of progression. CI, confidence interval. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

9 Supplementary Figure 1 Summary forest plot: comparison of pooled odds ratios of predictors of progression. CI, confidence interval. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

10 Supplementary Figure 1 Summary forest plot: comparison of pooled odds ratios of predictors of progression. CI, confidence interval. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

11 Supplementary Figure 1 Summary forest plot: comparison of pooled odds ratios of predictors of progression. CI, confidence interval. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

12 Supplementary Figure 1 Summary forest plot: comparison of pooled odds ratios of predictors of progression. CI, confidence interval. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

13 Supplementary Figure 1 Summary forest plot: comparison of pooled odds ratios of predictors of progression. CI, confidence interval. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

14 Supplementary Figure 2 Forest plot: predictors of progression to HGD/EAC. Studies reporting multivariate analysis adjusted for age and sex. CI, confidence interval; EAC, esophageal adenocarcinoma; HGD, high-grade dysplasia. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

15 Supplementary Figure 2 Forest plot: predictors of progression to HGD/EAC. Studies reporting multivariate analysis adjusted for age and sex. CI, confidence interval; EAC, esophageal adenocarcinoma; HGD, high-grade dysplasia. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions

16 Supplementary Figure 3 Forest plot: predictors of progression to HGD/EAC. Studies reporting multivariate analysis adjusted for age, sex, and BE characteristics (baseline dysplasia and/or BE length). BE, Barrett’s esophagus; CI, confidence interval; EAC, esophageal adenocarcinoma; HGD, high-grade dysplasia; LGD, low-grade dysplasia; NSAID, nonsteroidal anti-inflammatory drug; PPI, proton pump inhibitor. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2018 AGA Institute Terms and Conditions


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