Presentation is loading. Please wait.

Presentation is loading. Please wait.

Select: Molecular Pathology of Alzheimer's Disease

Similar presentations


Presentation on theme: "Select: Molecular Pathology of Alzheimer's Disease"— Presentation transcript:

1 Select: Molecular Pathology of Alzheimer's Disease
Cell  Volume 144, Issue 3, (February 2011) DOI: /j.cell Copyright © Terms and Conditions

2 β-amyloid induces AMPA receptor (AMPAr) dephosphorylation via a pathway involving caspase-3 (Casp-3) and calcineurin (CaN). Image courtesy of F. Cecconi. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

3 Tau proteins do not normally go to dendritic spines (red spines, triangles) but are mislocalized under disease conditions (yellow spines, arrows). Image courtesy of D. Liao. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

4 A theoretical graph shows the effects of increased production (red) or decreased clearance (blue) as possibilities for altered β-amyloid metabolism. Image courtesy of R. Bateman. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions


Download ppt "Select: Molecular Pathology of Alzheimer's Disease"

Similar presentations


Ads by Google