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Volume 59, Issue 4, Pages 814-829 (October 2013)
Management of chronic hepatitis B in childhood: ESPGHAN clinical practice guidelines Etienne M. Sokal, Massimiliano Paganelli, Stefan Wirth, Piotr Socha, Pietro Vajro, Florence Lacaille, Deirdre Kelly, Giorgina Mieli- Vergani Journal of Hepatology Volume 59, Issue 4, Pages (October 2013) DOI: /j.jhep Copyright © 2013 European Association for the Study of the Liver Terms and Conditions
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Fig. 1 Treatment algorithm for pediatric patients with CHB (modified from [1]). ∗Recommendation valid until results of ongoing trials on the treatment of immunotolerant children are available. ∗∗It is likely that PegIFN will replace IFN-α as the first-line treatment for CHB once the results of ongoing clinical trials are available. Journal of Hepatology , DOI: ( /j.jhep ) Copyright © 2013 European Association for the Study of the Liver Terms and Conditions
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Fig. 2 Response to antiviral treatments currently licensed for children: rates of virological (white bars), serological (HBeAg loss: light blue bars; HBeAg seroconversion: blue bars; HBsAg loss: dark blue bars) and biochemical (black bars) response in pediatric clinical trials. Entecavir has not been included as no pediatric trials have been conducted so far. Journal of Hepatology , DOI: ( /j.jhep ) Copyright © 2013 European Association for the Study of the Liver Terms and Conditions
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