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A Futile Approach to Fighting Obesity?

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Presentation on theme: "A Futile Approach to Fighting Obesity?"— Presentation transcript:

1 A Futile Approach to Fighting Obesity?
Shannon M. Reilly, Alan R. Saltiel  Cell  Volume 163, Issue 3, Pages (October 2015) DOI: /j.cell Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Different Modes of Mitochondrial Respiration
(A) Coupled respiration, which generates ATP. (B) Thermogenesis through uncoupled respiration by Ucp1, which does not involve ATP synthase. (C) Thermogenesis by creatine futile cycle, which requires ATP synthase activity, although no net ATP is generated. Cell  , DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions


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