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Spasmolytic effects of prostaglandin E1 on serotonin-induced bronchoconstriction and pulmonary hypertension in dogs  Y. Hashimoto, K. Hirota, H. Yoshioka,

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Presentation on theme: "Spasmolytic effects of prostaglandin E1 on serotonin-induced bronchoconstriction and pulmonary hypertension in dogs  Y. Hashimoto, K. Hirota, H. Yoshioka,"— Presentation transcript:

1 Spasmolytic effects of prostaglandin E1 on serotonin-induced bronchoconstriction and pulmonary hypertension in dogs  Y. Hashimoto, K. Hirota, H. Yoshioka, E. Hashiba, T. Kudo, H. Ishihara, A. Matsuki  British Journal of Anaesthesia  Volume 85, Issue 3, Pages (September 2000) DOI: /bja/ Copyright © 2000 British Journal of Anaesthesia Terms and Conditions

2 Fig 1 Effects of prostaglandin E1 on 5HT-induced pulmonary hypertension (A) and bronchoconstriction (B). Application of 5HT (10 μg kg− mg kg−1 h−1) is indicated by the solid bar. *, #, $ and + indicate P<0.05 and **, ##, $$ and ++ indicate P<0.01 compared with 0 (saline) and PGE1 0.01, 0.1 and 1.0 μg kg−1, respectively. All values are expressed as mean±sem. British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2000 British Journal of Anaesthesia Terms and Conditions


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