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Volume 90, Issue 6, Pages 1332-1341 (December 2016)
Hemodialysis patients receiving a greater Kt dose than recommended have reduced mortality and hospitalization risk Francisco Maduell, Rosa Ramos, Javier Varas, Alejandro Martin-Malo, Manuel Molina, Rafael Pérez-Garcia, Daniele Marcelli, Francesc Moreso, Pedro Aljama, Jose Ignacio Merello Kidney International Volume 90, Issue 6, Pages (December 2016) DOI: /j.kint Copyright © 2016 International Society of Nephrology Terms and Conditions
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Figure 1 Influence of hemodialysis treatment parameters for different categories of achieved–targetKt. The bars represent the percentage of patients on the HDF treatment option, left axis, for each adjusted Kt category. The squares (▪) represent the mean effective blood flow and the triangles (▴) the mean effective treatment time for the patients classified on each adjusted Kt category, right axis. Kidney International , DOI: ( /j.kint ) Copyright © 2016 International Society of Nephrology Terms and Conditions
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Figure 2 The analytical profiles for different categories of achieved–targetKt. (a) Albumin. (b) C-reactive protein. (c) Hemoglobin. *P < 0.05 by post hoc Scheffé test. Kidney International , DOI: ( /j.kint ) Copyright © 2016 International Society of Nephrology Terms and Conditions
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Figure 3 Death risk profiles for achieved–targetKt. Unadjusted (●) and adjusted (▪) analyses are shown. The HRs are compared with a common reference category (Ref.) for each analysis. The probability that each ratio is not different from its reference value is shown by a symbol near the ratio: # P < 0.001; × P < 0.01; + P < 0.05; no symbol means no significant differences. Bars = 95% confidence intervals. Kidney International , DOI: ( /j.kint ) Copyright © 2016 International Society of Nephrology Terms and Conditions
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Figure 4 Hospitalization risk profiles for achieved–targetKt groups. Unadjusted (●) and adjusted (▪) analyses are shown. The HRs are compared with a common reference category (Ref.) for each analysis. The probability that each ratio is not different from its reference value is shown by a symbol near the ratio: # P < 0.001; × P < 0.01; + P < 0.05; no symbol means no significant differences. Bars = 95% confidence intervals. Kidney International , DOI: ( /j.kint ) Copyright © 2016 International Society of Nephrology Terms and Conditions
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Figure 5 Proposal to improve survival by increasing the target Kt to +1 to +3 L achieved–targetKt. Unadjusted (●) and adjusted (▪) analyses are shown. The HRs are compared with a common reference category (Ref.) for each analysis. The probability that each ratio is not different from its reference value is shown by a symbol near the ratio: # P < 0.001; × P < 0.01; + P < 0.05; no symbol means no significant differences. Bars = 95% confidence intervals. Kidney International , DOI: ( /j.kint ) Copyright © 2016 International Society of Nephrology Terms and Conditions
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