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Peptidergic nociceptor markers are reduced in DRG from Nav-Tsc2 mice.
Peptidergic nociceptor markers are reduced in DRG from Nav-Tsc2 mice. Immunohistochemisty of adult L4 DRG transverse sections stained for SP and TuJ1 (A, B) or NF200 and CGRP (D, E), NF200 and TrkA (G, H), or NF200 and IB4 (J, K). Scale bar: 100 µm. Arrows point to neurons that colabeled with NF200. C, F, G, L, Total number of L4 DRG neurons labeling with markers as indicated. Individual animals plotted with mean ± SEM; N = 4-6; N.S. p > 0.05, **p < 0.01, ***p < 0.001, ****p < Dan Carlin et al. eNeuro 2018;5:ENEURO ©2018 by Society for Neuroscience
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