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Extratumoral Vascular Invasion Is a Significant Prognostic Indicator and a Predicting Factor of Distant Metastasis in Non-small Cell Lung Cancer Yoshihisa Shimada, MD, Genichiro Ishii, MD, Tomoyuki Hishida, MD, Junji Yoshida, MD, Mitsuyo Nishimura, MD, Kanji Nagai, MD Journal of Thoracic Oncology Volume 5, Issue 7, Pages (July 2010) DOI: /JTO.0b013e3181dd1803 Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions
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FIGURE 1 Vascular invasion in a Victoria blue van Gieson (VvG)-stained section of non-small cell lung cancer. These figures show intratumoral vascular invasion (v1) within a tumor nest in hematoxylin and eosin (HE) staining (A; arrow) and VvG staining (B). Findings of extratumoral vascular invasion (v2) in HE staining (C; arrow head) and VvG staining (D) are shown. Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181dd1803) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions
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FIGURE 2 A, Kaplan-Meier recurrence-free survival curve for patients with non-small cell lung cancer (NSCLC) according to a qualitative definition of vascular invasion (v0 versus v1 versus v2). B, Kaplan-Meier overall survival curve for patients with NSCLC according to a qualitative definition of vascular invasion (v0 versus v1 versus v2). Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181dd1803) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions
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