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Atypical Thymoma (World Health Organization Type B3) with Neuroendocrine Differentiation Combined with Hyperparathyroidism  Hyun Sik Park, MD, Sang Wha.

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Presentation on theme: "Atypical Thymoma (World Health Organization Type B3) with Neuroendocrine Differentiation Combined with Hyperparathyroidism  Hyun Sik Park, MD, Sang Wha."— Presentation transcript:

1 Atypical Thymoma (World Health Organization Type B3) with Neuroendocrine Differentiation Combined with Hyperparathyroidism  Hyun Sik Park, MD, Sang Wha Lee, MD, Seon Ung Yun, MD, Byeong Joo Bae, MD, Hye Jin Choi, MD, So Young Kim, MD, Hae Jin Choi, MD, Wan Seop Kim, MD, Hee Joung Kim, MD, Kye Young Lee, MD  Journal of Thoracic Oncology  Volume 5, Issue 9, Pages (September 2010) DOI: /JTO.0b013e3181e04416 Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Chest CT-scan showing 43-mm sized mediastinal mass having irregular margined, slightly high density, with slightly enhancing soft tissue mass on anterior mediastinum. CT, computed tomography. Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181e04416) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 A, H&E staining, tumor cells are polygonal, medium to large sized, and have the prominent nucleoli. There are a few intraepithelial lymphocytes forming sheets. B, Immunohistochemical stain, the tumor cells are strong positive for synaptophysin. C, Negative for parathyroid hormone stain on immunohistochemical stain. D, Cut surface of the tumor, grossly, there is a grayish white, ill defined, and lobulating mass. It is composed of firm mass with fibrous septum and infiltrates into the surrounding mediastinal fat. H&E, hematoxylin and eosin. Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181e04416) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

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