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Histologic similarities in children with eosinophilic esophagitis and proton pump inhibitor–responsive esophageal eosinophilia  Nathalie Nguyen, MD, Anna.

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Presentation on theme: "Histologic similarities in children with eosinophilic esophagitis and proton pump inhibitor–responsive esophageal eosinophilia  Nathalie Nguyen, MD, Anna."— Presentation transcript:

1 Histologic similarities in children with eosinophilic esophagitis and proton pump inhibitor–responsive esophageal eosinophilia  Nathalie Nguyen, MD, Anna Baumgarten, MD, Benjamin L. Wright, MD, Kelley E. Capocelli, MD, Zhaoxing Pan, PhD, James J. Lee, PhD, Glenn T. Furuta, MD, Joanne C. Masterson, PhD  Journal of Allergy and Clinical Immunology  Volume 143, Issue 3, Pages e2 (March 2019) DOI: /j.jaci Copyright © Terms and Conditions

2 Fig 1 Scores for each EPX histology parameter including (A) reproducibility (extent of all biopsies with eosinophil infiltration or degranulation), (B) patchiness (extent of eosinophil infiltration or degranulation in maximally affected biopsy), (C) level of degranulation, (D) maximum eosinophils in a single focus, (E) average number of eosinophils in five 40× hpfs, and (F) total EPX score (EoE n = 24, PPI-REE n = 9, GERD n = 28, and controls n = 22). n.s., Not significant. *P < .05; ****P < .0001. Journal of Allergy and Clinical Immunology  , e2DOI: ( /j.jaci ) Copyright © Terms and Conditions


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