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Diffuse Alveolar Hemorrhage Temporally Related to Cocaine Smoking

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Presentation on theme: "Diffuse Alveolar Hemorrhage Temporally Related to Cocaine Smoking"— Presentation transcript:

1 Diffuse Alveolar Hemorrhage Temporally Related to Cocaine Smoking
Richard J. Murray, M.D., Robert J. Albin, M.D., Wolfgang Mergner, M.D., Gerard J. Criner, M.D.  CHEST  Volume 93, Issue 2, Pages (February 1988) DOI: /chest Copyright © 1988 The American College of Chest Physicians Terms and Conditions

2 Figure 1 Admission PA chest radiograph. Bilateral alveolar infiltrates are present with predominantly lower lobe involvement. The cardiac silhouette is normal in size. CHEST  , DOI: ( /chest ) Copyright © 1988 The American College of Chest Physicians Terms and Conditions

3 Figure 2 Lung tissue with intraalveolar hemorrhage and marked proliferation of type 2 pneumocytes. Note the intraalveolar and interstitial macrophages. There is no evidence of vasculitis. (H and E, original magnification, 250X.) A = Intraalveolar; I = interstitial. Inset—Lung tissue in less involved area. Note the focal septal enlargement. (H and E, original magnification, 40X.) CHEST  , DOI: ( /chest ) Copyright © 1988 The American College of Chest Physicians Terms and Conditions

4 Figure 3 Electron photomicrograph of the alveolar septum. Note two type 2 pneumocytes and an intra-alveolar red blood cell. There is septal fibrosis. Two macrophages are noted in the septum containing pigment (Uranyl acetate and lead citrate, original magnification, 3000X.) col = collagen; pH = type 2 pneumocytes; mac = macrophage. CHEST  , DOI: ( /chest ) Copyright © 1988 The American College of Chest Physicians Terms and Conditions


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