1. Vitamin D3 levels alter amphetamine-related behaviors in mice.
Vitamin D3 levels alter amphetamine-related behaviors in mice. A, Binned locomotor activity of HF and HF-D mice during habituation, saline injection (black arrow), and acute amphetamine treatment (red arrow). B, HF and HF-D cumulative activity for 20 min after amphetamine administration (n = 5, 5). C, D, Binned locomotor activity of Ch and Ch-D mice during habituation, saline injection (black arrow), and acute amphetamine treatment (red arrow; C), and Ch and Ch-D cumulative activity for 2 h after amphetamine (n = 4, 4; D). E, Binned locomotor activity in naïve mice pretreated with vehicle or calcitriol (n = 8, 8) 6-7 h prior to acute amphetamine treatment (red arrow). F, Cumulative activity of the pretreated mice over 2 h after amphetamine administration.
Joseph R. Trinko et al. eneuro 2016;3:ENEURO
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