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Oksana Sulaieva, Victoriia Deliy, Stanislav Zharikov  Pathophysiology 

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Presentation on theme: "Oksana Sulaieva, Victoriia Deliy, Stanislav Zharikov  Pathophysiology "— Presentation transcript:

1 Relationship between leukocytes recruitment and risk of rebleeding in patients with peptic ulcers 
Oksana Sulaieva, Victoriia Deliy, Stanislav Zharikov  Pathophysiology  Volume 22, Issue 4, Pages (December 2015) DOI: /j.pathophys Copyright © Terms and Conditions

2 Fig. 1 Elevation of PMN count in the ulcer margin of patients with a sustained hemostasis (1st group) and rebleeders (2nd group). A – Chart demonstrates PMN count in adjacent to ulcer tissues among patients of the 1st and 2nd groups at the time of their hospital admission (Me±m; CI). B – Ischemia and inflammation in the gastric ulcer margin among patients of the 1st group. C – Deep infiltration of gastric mucosa with PMNs among patients of the 2nd group. H&E staining. Pathophysiology  , DOI: ( /j.pathophys ) Copyright © Terms and Conditions

3 Fig. 2 Macrophages density in ulcer margin among patients with acute ulcer bleeding. A – Chart demonstrates PMN count in adjacent to ulcer tissues among patients of the 1st and 2nd groups at the time of their hospital admission (Me±m; CI). B – Histological specimens of marginal zone of ulcer of the 1st group patients under immunohistochemistry (CD 68). С and D – Increased number of macrophages in the gastric (C) and duodenal (D) ulcer margin among patients of the 2st group. Immunohistochemistry (CD68). Pathophysiology  , DOI: ( /j.pathophys ) Copyright © Terms and Conditions

4 Fig. 3 Impact of leukocytes on platelets’ aggregation induced with collagen among patients with acute ulcer bleeding (%). Description: the collagen-induced platelet aggregation (%) is shown under different conditions: when platelets were incubated with collagen alone (Pl) or under preliminary co-incubation of platelets with leukocytes (Pl+Lc). Pathophysiology  , DOI: ( /j.pathophys ) Copyright © Terms and Conditions


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